Gene name:
Lipa (Lal;Lip1) ;
Protein name:
Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase;LAL) ;
Alternative:
Lipase A ;Cholesteryl esterase ;Sterol esterase ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Subcellular Location:
Lysosome
Protein Attributes:
50:
MQLLGRVICF | VVGILLSGGP | TGTISAVDPE | ANMNVTEIIM | HWGYPEHSVQ |
100:
TGDGYILGVH | RIPHGRKNQF | DKGPKPVVYL | QWRHGFLADS | SNWVTNIDNN |
150:
SLGFILADAG | FDVWMGNSRG | NTWSRKHKTL | SVSQDEYWAF | SFDEMAKYDL |
200:
PASINYILNK | TGQEQLYNVG | HSQGCTIGFI | AFSQMPELAK | KVKMFFALAP |
250:
VLSLNFASGP | MVKLGRLPDL | LLEDLFGQKQ | FLPQSAMVKW | LSTHICTHVI |
300:
MKELCANIFF | LICGFNEKNL | NMSRVDVYTT | HCPAGTSVQN | MVHWTQVVKY |
350:
HKLQAFDWGS | SDKNYFHYNQ | SYPPLYSIKD | MQLPTALWSG | GKDWLADTSD |
397:
INILLTEIPT | LVYHKNIPEW | DHLDFIWGLD | APWRLYNEVV | SLMKKYQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Rat Acid cholesteryl ester hydrolase
ELISA Kit for Rat Acid cholesteryl ester hydrolase
ELISA Kit for Rat Acid cholesteryl ester hydrolase
CLIA Kit for Rat Acid cholesteryl ester hydrolase
CLIA Kit for Rat Acid cholesteryl ester hydrolase
CLIA Kit for Rat Acid cholesteryl ester hydrolase
Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
Protein for Rat Acid cholesteryl ester hydrolase
Protein for Rat Acid cholesteryl ester hydrolase
Protein for Rat Acid cholesteryl ester hydrolase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .